

Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonate
CAS No. 68-89-3
Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonate( Dipyrone )
Catalog No. M15634 CAS No. 68-89-3
A drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of aminopyrine.
Purity : >98% (HPLC)






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5MG | 49 | In Stock |
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25MG | 111 | In Stock |
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50MG | 162 | In Stock |
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100MG | 227 | In Stock |
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Biological Information
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Product NameSodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonate
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NoteResearch use only, not for human use.
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Brief DescriptionA drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of aminopyrine.
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DescriptionA drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of aminopyrine. Because of the risk of serious adverse effects its use is justified only in serious situations where no alternative is available or suitable.
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In VitroCell Proliferation Assay Cell Line:PaTu 8988 t, Panc-1 Concentration: 1, 10, 100, 250, 500 μM Incubation Time:48 hours Result:Inhibited proliferation in the PaTu 8988 t cell line with 1–500 μM and with concentrations of 1 μM,10 μM, 100 μM, and 250 μM in the Panc-1 cell line.Increased the apoptosis rate after 9 h.
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In VivoAnimal Model:Male Wistar rats (270-300 g), with peripheral neuropathic painDosage:500 mg/kg Administration:Intraperitoneal injection, twice a day, for 7 days Result:Diminished the expression of pronociceptive interleukins (IL-1beta, IL-6, and IL-18) and chemokines (CCL2, CCL4, and CCL7) in DRG measured 7 days after sciatic nerve injury.Animal Model:Pain model in rats Dosage:250 or 500 mg/kg Administration: p.o.Result:Decreased the COX-2 gene expression at 500 mg/kg and increased the MPO gene expression.Reduced MDA levels in the carrageenan paw test and increased tGSH levels.
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SynonymsDipyrone
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX-1
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number68-89-3
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Formula Weight333.34
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Molecular FormulaC13H16N3NaO4S
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=S(CN(C1=C(C)N(C)N(C2=CC=CC=C2)C1=O)C)([O-])=O.[Na+]
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Chemical NameMethanesulfonic acid, ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)-, sodium salt
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jage J, et al. Anaesthesist. 2008 Apr;57(4):382-90.
molnova catalog



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